Immunochemical Analysis Shows All Three Domains of Diphtheria Toxin Penetrate across Model Membranes
نویسندگان
چکیده
منابع مشابه
a comparative pragmatic analysis of the speech act of “disagreement” across english and persian
the speech act of disagreement has been one of the speech acts that has received the least attention in the field of pragmatics. this study investigates the ways power relations, social distance, formality of the context, gender, and language proficiency (for efl learners) influence disagreement and politeness strategies. the participants of the study were 200 male and female native persian s...
15 صفحه اولDiphtheria Toxin In
Recent studies have demonstrated that diphtheria toxin is an enzyme of unusual type. Small amounts of the toxin, added to nicotinamide adenine dinucleotide (NAD)-containing mammalian cell extracts, block peptide-bond formation by catalyzing inactivation of the translocating enzyme, aminoacyltransferase 2 (T2) (1-3). This highly specific reaction involves the splitting of NAD with liberation of ...
متن کاملThe Production of Diphtheria Toxin
Toxin of sufficient strength to kill a 400-gramme guinea-pig in three days and a half in a dose of 0.cubic centimetre developed in suitable bouillon, contained in ordinary Erlenmeyer flasks, within a period of twenty-four hours. In such boullon the toxin reached its greatest strength in from four to seven days (0.005 cubic centimetre killing a 500-gramme guinea-pig in three days). This period o...
متن کاملPotency of a Human Monoclonal Antibody to Diphtheria Toxin Relative to Equine Diphtheria Anti-toxin in an Animal Model
116. Potency of a Human Monoclonal Antibody to Diphtheria Toxin Relative to Equine Diphtheria Anti-toxin in an Animal Model Heidi Smith, MD, PhD; Peter Cheslock, PhD; Mark Leney, PhD; Bruce Barton, PhD; Deborah Molrine, MD; MassBiologics of the University of Massachusetts Medical School, Boston, Massachusetts; Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, ...
متن کاملPaxDb, a Database of Protein Abundance Averages Across All Three Domains of Life*
Although protein expression is regulated both temporally and spatially, most proteins have an intrinsic, "typical" range of functionally effective abundance levels. These extend from a few molecules per cell for signaling proteins, to millions of molecules for structural proteins. When addressing fundamental questions related to protein evolution, translation and folding, but also in routine la...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1995
ISSN: 0021-9258
DOI: 10.1074/jbc.270.46.27446